Acronym in Italian standing for Innovative Methods and Instruments in Rehabilitation Medicine for the outcomes of Severe Acquired Brain Injuries.
The objective of the MIMERICA project concerned the definition, development and testing of innovative methodologies and tools to support clinicians in the management of rehabilitation processes for patients with severe acquired brain injuries.

These are the achievements of the Mimerica project:

• ARAMIS: For years, research on robotics has begun for the rehabilitation of the hemiplegic patient. Aramis has been built, a double exoskeleton for the upper limb recovery in stroke patients that has obtained a European patent. Eight years of research and two of experimentation are showing significantly better results than traditional rehabilitation.


With the TELEGCA project, Istituto S. Anna intended to start a program aimed at defining new info-telematic services applied to recovering the functions after severe acquired brain injuries (GCA). In particular, Hardware and Software systems have been developed and tested to provide online health services concerning the teleconsultation, tele-assistance, tele-monitoring and remote rehabilitation.


PROCEDURES AND HW AND SW SYSTEMS FOR TELEMEDICINE (Teleconference with the Departments of the Provincial Health Centres that send the patients; Teleassistance with the patients at home)


Model for the integrated management and assistance of chronic patients in VS (vegetative state) and MCS (minimally conscious state) in the Calabria Region. The project was presented by the Calabria Region for the objectives of priority nature and of national importance. It received the approval of the Ministry of Health in May 2010. A project aimed at activating a management experimentation, unique in Italy and in Europe, for the assistance of chronic patients in Vegetative State (SV) and Minimally Conscious State (SMC) on the entire regional territory of Calabria. For the implementation of the activities envisaged in the various phases of the Executive Plan, the Provincial Health Centres of Crotone was identified as the leader and Istituto S. Anna di Crotone as the executor. The implementation of the project took place within a public-private management experimentation, as provided and regulated by Art. 9 bis of Legislative Decree 502 of date 20 December 1992. The specialised long-term care of Istituto S. Anna guarantees a clinical assistance service whose model has been considered as a national and international reference on several occasions. The Plan has defined an integrated service for chronic patients in a vegetative state and minimally conscious state with different aetiology that has provided:

assistance to patients in a vegetative state and minimally conscious state in the Institute’s Long-term Care Unit that, starting from the current protocols, is further improved with the use of procedures and systems for the automated monitoring of biometric parameters and for the assessment of the state of consciousness;

assistance to patients in a vegetative state and minimally conscious state at their home through telemedicine services and a remote Integrated Home Assistance team. The main objective is to develop a model of care that, by exploiting the experience and expertise acquired for the treatment of the aforementioned patients, is able to satisfy, in a logic of efficiency, the entire regional requirement and that is a reference to the scientific community for the cutting-edge applications it is planning to implement.
The realisation of the activities aims at achieving the following objectives:
• improvement of individual treatments for patients in a vegetative state and minimally conscious state in the long-term hospitalisation at the Long-term Care Unit;

• facilitating and spreading the practice of home care in safe conditions, with a great relief for families;

• increase in the professionalism of medical staff, social workers, nurses, carers and, in general, those people that, for professional reasons are in contact with patients at their homes;

• full and widespread coverage in the regional territory of the need for assistance for chronic patients in a vegetative state and minimally conscious state with different aetiology;

• decrease in patients admitted to hospital in the long term at the Long-term Care Wards with a consequent increase in the number of patients at home;

• facilitation of the transition of patients from the vegetative state to the minimally conscious state.


• Optimisation of Long-term Care procedures

• Home Hospitalisation Service


A project to develop advanced technologies and systems to support the processes of diagnosis, prognosis and functional recovery or containment of the damage in subjects with severe acquired brain injury (vegetative states and minimally conscious states, results of stroke or cranioencephalic traumas) or deficiency from chronic diseases of the MCSN nervous system (Parkinson, Alzheimer’s and multiple sclerosis); provides the defining, development and experimentation of new techniques and methodologies in the clinical field and of innovative robomatronic and virtual reality systems/devices.

The results obtained are:

• Optimised procedures in wards that treat patients with more or less severe CG outcomes;

• Systems for the analysis and processing of unit’s data aimed at acquiring new knowledge;

• Studies in functional MRI of post-stroke patients

• Robotic systems (4MO, Intellibed, MotionRehab@Home; MotionRehabLAB, etc.) and innovative devices (Copernicus, Polyphemus, SMS-SensoryMulti Stimulator) for the recovery and rehabilitation of patients with motor and cognitive-behavioural deficits)


“Development of innovative processes and support services for the early diagnosis of motor, behavioural and memory disorders in Parkinson’s disease and Alzheimer’s dementia for the measurement and optimisation of recovery/rehabilitation in patients with severe acquired brain injuries and stroke”.

The project aims at implementing innovative processes and support services for the early diagnosis of Parkinson’s disease and Alzheimer’s dementia and of specific motor, behavioural and/or memory disorders that are typical of these pathologies.
NEUROMEASURES fits into an innovative scientific context with the aim of integrating the current knowledge of biomarkers that help characterise the main clinical symptoms of Parkinson’s disease and Alzheimer’s dementia, with the knowledge deriving from modern neurosciences that propose new physiopathological scenarios.
We intend creating new behavioural and advanced neuroimaging prototypes, based on “Virtual Reality” technologies and “Data Fusion” methodologies and services, with the scope of extracting diagnostic information related to the diseases under study and to rework the management of innovative processes for the early diagnosis of Parkinson’s disease and Alzheimer’s dementia. The project will also develop new decision support services for the early diagnosis of Parkinson’s disease and Alzheimer’s dementia through the use of advanced computational tools, with particular reference to Machine Learning techniques.
The expected result of this activity is an innovative product of considerable importance in clinical practice in terms of a support tool in accurate and early diagnostic processes, based on the identification of new neuroimaging, behavioural and molecular markers.
The project also intends to define, develop and implement an integrated system for objective quantitative assessment, recovery prognosis and optimisation of the rehabilitation path in patients with severe acquired brain injuries, stroke, Parkinson’s disease and cognitive decline.